The binding of isaac bosses5/27/2023 Anthropomorphic Personification: They're humanoid personifications of their respective sins.The implication that every character is an alternate Isaac as he only imagined the events of the gameplay just complicates things further. Mega gives him Wrath's "mask", humanoid monsters from the start, or the actual Sins themselves given physical embodiment. Ambiguously Human: It's not clear if they are humans under the effect of various items note The Virus makes Isaac resemble Lust without the pink coloration and Mr.Debut (Super variants and Ultra Pride): Wrath of the Lamb
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